When considering taking ZERODOL SP with other medications, it's essential to consult with a healthcare professional. This medication contains Aceclofenac, an NSAID, which can interact with other drugs, potentially increasing the risk of side effects or reducing effectiveness. For example, combining it with other NSAIDs or blood thinners may increase the risk of bleeding. Always inform your doctor about all medications and supplements you are currently taking to ensure safe and effective treatment.