GLP-1 medicines can interact with various other medications, which is why it's essential to inform your healthcare provider about all the drugs you are taking. For instance, they may affect the absorption of oral medications, particularly those that require a specific stomach environment to be effective. Additionally, combining GLP-1s with other diabetes drugs may increase the risk of low blood sugar (hypoglycemia). Always consult your GP or pharmacist before starting new medications while on GLP-1 therapy to ensure safe and effective treatment.