GLP-1 medicines and insulin are both used to manage blood sugar levels, but they work in different ways. GLP-1 medicines mimic the action of a hormone called glucagon-like peptide-1, which helps lower blood sugar by stimulating insulin release and slowing gastric emptying. They are typically used for Type 2 diabetes and can assist with weight loss. On the other hand, insulin is a hormone that directly lowers blood sugar levels by allowing cells to absorb glucose. Insulin is crucial for people with Type 1 diabetes and may also be required by some with Type 2 diabetes. In summary, while both help control blood sugar, GLP-1s have additional benefits such as weight management, which insulin does not provide.